Real World Evidence (RWE)

Real world data (RWD) refers to health data that can be used, for example, to demonstrate the value of a certain treatment or technology for patients, healthcare service providers or society (RWE). Due to comprehensive healthcare, data in digital format, a personal ID, and progressive research legislation, Finland is a true model country for Real World Evidence studies. 

Medaffcon has the most extensive experience in analyzing and utilizing real world data (RWD) in Finland. We have been conducting RWE studies since 2013 when the Biobank Act came into effect and allowed for more extensive use of the data when conducting research. Our RWE-studies are closely related to the health economics perspective on the cost-effectiveness of interventions. Also, we are closely involved in supporting and developing unique information sources in Finland. 

We provide individually tailored RWE research services to different healthcare actors, where our scientific experts and bioinformatics ensure that the correct research methods and data sources are used to answer your questions. 

Medaffcon’s RWE studies have gathered new knowledge in different therapeutic areas, including: 

  • Disease burden of different patient groups
  • Use of healthcare resources
  • Diagnostics of rare diseases
  • Treatment lines and outcomes
  • Mortality
  • Characteristics of patient subgroups
  • Outlining regional treatment practices
  • Cost-effectiveness

 

Read more about our publications

More information on RWE-studies and the opportunities they can bring to us can be found on our Future Care Finland website

”As a biostatistician, I know the statistical methods and how they can be utilized in data analysis. I’m familiar with the different data sources, their potential and limitations. My job is to process and analyze raw data, and to provide statistical evidence for the customer in response to burning questions, to support decision-making, and to fill in data gaps”
Iiro Toppila
Biostatistician & Data Analysis Lead, Medaffcon Oy
”The number of RWE studies has increased since stakeholders within the healthcare industry have an increasing demand for knowledge-based decision making tools that needs to be fulfilled. The future; therefore, has an ever-increasing emphasis on RWE.”
Mariann Lassenius
Sr. Scientific Advisor & RWE Lead, Medaffcon Oy
”RWE complements our understanding of the effectiveness of interventions and resource use in the Finnish population, thereby reducing uncertainty in health-economic modeling.”
Tatu Sainio
Sr. Health Economist & Access & HE Lead, Medaffcon Oy

We are more than happy to tell you more!

Mariann Lassenius
Sr. Scientific Advisor
RWE Lead

Contact us

Our Real World Evidence Experts:

Mariann Lassenius
Sr. Scientific Advisor
RWE Lead

Mariann Lassenius

Sr. Scientific Advisor
RWE Lead
PhD

+358 50 345 2393 LinkedIn

Mariann joined Medaffcon’s team in 2016 after finishing her PhD. The transition to real world evidence (RWE) research was a natural continuum to her previous research career. Through RWE studies, she has had the privilege to gain a broad insight into working with different stakeholders within the healthcare field. The vast proportion of her days goes towards interacting with clients, planning and performing RWE studies, and supporting Medaffcon’s RWE team. Subjects that keep her work interesting are the vast variability of customers and projects, problem-solving, and interacting with people.

“The number of RWE studies has increased since stakeholders within the healthcare industry have an increasing demand for knowledge-based decision making tools that need to be fulfilled. The future, therefore, has an ever-increasing emphasis on RWE”.


Jaana Ahlamaa
Medical Director

Jaana Ahlamaa

Medical Director
MD (Specialist in Surgery), PhD

+358 50 576 7325 LinkedIn

Jaana established Medaffcon in 2009. Prior to that, she worked in expert and management positions in the pharmaceutical industry for almost ten years. Jaana has also worked as a hospital doctor and is a specialist in surgery. In 1999, she defended her doctoral thesis on health policy related to customer payments in healthcare.

Jaana’s most essential contribution to Medaffcon’s team is her wide-ranging experience and expertise. Jaana is particularly interested in the future development of the Finnish healthcare sector. In particular, the use of knowledge in decision-making and new opportunities brought by digitalization fascinates Jaana. “I am especially looking forward to how we can improve personalized treatment options in healthcare and systematically evaluate the effectiveness and cost-effectiveness of treatments”.


Päivikki Hemmilä
Scientific Advisor

Päivikki Hemmilä

Scientific Advisor
PhD

+358 45 120 0632 LinkedIn

Päivikki joined Medaffcon’s team in September 2017. She has a PhD in cancer biology. Päivikki worked for the first 10 years of her career as a cancer researcher. Following her career in research, Päivikki has worked in different specialist positions in sales, research, quality and registration fields in pharmaceutical, medical device and CRO companies. Before joining Medaffcon, Päivikki worked in the Finnish Clinical Biobank Tampere, where she was responsible for the construction and development of the biobank’s quality system and operational processes.

Päivikki works as a scientific advisor in Medaffcon, where her extensive experience as a project leader, combined with strong scientific expertise, can be utilized in various client projects. Päivikki is fascinated by the continuous development of the healthcare industry as a result of cooperation between different actors. “It’s really interesting to see how the utilization of real-world data is evolving due to the possibility to access new data sources and due to changes in legislation”.


Sanna Honkala
Scientific Advisor

Sanna Honkala

Scientific Advisor
PhD

+358 50 327 3440 LinkedIn

Sanna joined Medaffcon’s team in November 2019. In her PhD, she studied the potential of high-intensity interval training (HIIT) in the prevention and management of type 2 diabetes. After defending her PhD in 2018, she worked as a post-doctoral researcher at the University of Turku. In addition, Sanna has experience working as an entrepreneur in the field of work-wellbeing. As a base-education, she has two master’s degrees (Biomedicine and Exercise Physiology).

Sanna’s strengths include strong expertise in science, diverse educational background, excellent management skills and above all, her positive nature. She is fascinated by the dynamics and endless innovative opportunities in the healthcare industry. “It is extremely interesting to see how individual treatment paths can be tailored in the future for example based on the genome or different biomarkers. In addition, new digital solutions in the prevention and management of different diseases will surely improve health and the daily lives of many individuals”.


Tanja Nieminen
Health Economist & Scientific Project Manager

Tanja Nieminen

Health Economist & Scientific Project Manager
M.Sc. (Health Economics & Economics)

+358 50 328 6651 LinkedIn

Tanja joined Medaffcon’s team in November 2016. Before that, she worked as a researcher at the National Institute for Health and Welfare. Tanja has also worked in an international research group, as a course instructor as well as in financial administration and customer service. She holds MSc degrees in both Health Economics and in the field of Economics and Business Administration.  

Tanja’s strengths include her educational and occupational background in health economics from Finland and abroad. Tanja has a special interest in utilizing real-world evidence data to be used in evaluations. “By utilizing data resources to support decision-making we become more aware of how scarce resources should be allocated”. 


Tatu Sainio
Sr. Health Economist
Access & HE Lead

Tatu Sainio

Sr. Health Economist
Access & HE Lead
M.Sc. (Economics & Health Economics)

+358 44 530 5525 LinkedIn

Tatu joined Medaffcon in the fall of 2016. Tatu holds two master’s degrees, majoring in Marketing and Health Economics. Before joining Medaffcon, he worked in the pharmaceutical industry at Boehringer Ingelheim as an Account Manager. At Medaffcon, Tatu works mainly with health technology assessments and is the access & health economics team lead. Through his educational and professional background, Tatu has a wide range of expertise in the pharmaceutical industry and understands the needs of each function.

Tatu’s strength is his comprehensive understanding of the pharmaceutical industry and healthcare environment. Tatu is particularly interested in the possibility to turn data into understandable information to support healthcare decision-making.

“I love the hype around the utilization of real-world effectiveness and cost-effectiveness data. Now we need steps to include the data as a systematic part of the decision-making process, which allows the optimal allocation of resources”.


Milla Summanen
Scientific Advisor

Milla Summanen

Scientific Advisor
PhD

+358 45 238 0122 LinkedIn

Milla started at Medaffcon in February 2019. Milla obtained her PhD in cell biology from Utrecht University in the Netherlands. From 2014 until 2019 she worked as a postdoctoral researcher at the Laboratory of Neurobiology at the University of Helsinki.

Milla’s strengths include a solid scientific background, excellent organizational skills, and a diverse and international educational background. Milla is especially interested in working with clinically relevant scientific data, in the possibilities of precision medicine, and in collaborating with the different stakeholders of the health care sector. “I believe that the importance of real-world evidence studies will increase, and the research results can be used to improve individual treatment paths in the future.”


Iiro Toppila
Biostatistician
Data Analysis Lead

Iiro Toppila

Biostatistician
Data Analysis Lead
M.Sc. (Tech.)

+358 44 314 1597 LinkedIn

Iiro joined Medaffcon in March 2017 as a Biostatistician. For the preceding four years, he has worked as a research assistant in an academic study group, analyzing clinical and genetic patient data. Iiro holds a Master of Science degree in Technology in Bioinformation Technology.

Iiro’s strengths include his strong expertise in statistics and data-analysis, hands-on experience in working with sensitive patient data, and strong interdisciplinary communication skills with experts from various fields. In the field, he is particularly interested in the large data amounts made available with the revolution of technology and how the information received such data can potentially be utilized to draw concrete conclusions, both in order to understand the nature of diseases and to advance the goals of the pharmaceutical industry and patient treatment.

“Machine learning and AI-based solutions will have a major impact on the healthcare sector now and in the future. However, effectively utilizing the already collected and available health-data will have a higher importance in order to improve health-care”.


Samuli Tuominen
Data Scientist

Samuli Tuominen

Data Scientist
M.Sc. (Statistics)

+358 40 520 8158 LinkedIn

Samuli joined Medaffcon in November 2018. He acquired a master’s degree in Statistics at the University of Helsinki, specializing in Bioinformatics in September 2018. Before joining Medaffcon, Samuli had two years’ worth of experience in research as a research assistant at the University of Helsinki, where he contributed to unraveling the genetic and epigenetic background of psychological characteristics (Depsy-group).

Samuli is especially interested in producing influential research data based on information on real-world patients. He is also interested in applying varying statistical and machine learning methods. Samuli has a broad theoretical and methodological understanding, as well as experience in working with big data. He is a problem solver and has an analytical take on work.

“I see that the health sector is being transformed by digitalization. I am excited to further develop the new opportunities made possible by the automated collection of patient data”.


Werneri Tuompo
Jr. Scientific Project Manager

Werneri Tuompo

Jr. Scientific Project Manager

+358 44 041 7670 LinkedIn

Werneri joined Medaffcon’s Medical team as a trainee in November 2017. He has a Bachelor of Science degree in Biomedicine. In addition to his work, Werneri is currently undertaking two different master’s degrees: in Biomedicine and Wellness Technology. As a young employee, Werneri brings fresh perspectives from his university studies and applies these to his practical work. In the field, he is interested in constantly changing circumstances, multi-professional working environment, and the possibilities digitalization offers when improving health.


Elisa Tyynysniemi
Scientific Project Manager

Elisa Tyynysniemi

Scientific Project Manager
M.Sc. (Pharmaceutical Science)

+358 40 839 4369 LinkedIn

Elisa joined Medaffcon’s team in January 2015. Before that, Elisa studied Biomedicine at the University of Turku and completed a master’s degree in a program for international drug development at the University of Copenhagen. She has worked as a researcher at the Department of Pathology of the University of Turku, marketing authorization coordinator at the Finnish Medicines Agency, Fimea, and in pharmacovigilance positions in Copenhagen. At Medaffcon, Elisa has worked as a scientific expert in various client companies and, among other things, written scientific reviews and therapeutic values.

Elisa brings an extensive background in medicine, pharmacy, and economics to Medaffcon. In the pharmaceutical industry, she is interested in the seamless co-operation between different mission profiles and working towards common goals. Elisa is particularly interested in the digitalization of science and knowledge management. “It is exciting to see how different clients utilize digital platforms in order to share information and to improve patient safety”.


Kristiina Uusi-Rauva
Scientific Advisor

Kristiina Uusi-Rauva

Scientific Advisor
PhD

+358 40 047 3314 LinkedIn

Kristiina joined Medaffcon’s RWE team in the fall of 2019. She holds a PhD and her doctoral dissertation concentrated on cell biology of a rare neurological disease. After defending her PhD, Kristiina worked on projects using iPS cell technology in several different research groups for rare diseases. In addition, she has experience in the most common diseases, as she has worked with diabetic research, for example.

“In this work, we can see from the field how know-how is effectively acquired and for what purposes it is used in healthcare. I look forward to seeing the full potential of biobank sample collections for future use in RWE research, including rare diseases”.