Selected Publications by Medaffcon Oy

These articles, posters and study abstracts represent a subset of the biobank and other real world evidence -based studies conducted by Medaffcon.


Peer-reviewed articles

The burden of adult asthma in Finland: impact of disease severity and eosinophil count on health care resource utilization, Viinanen A, Lassenius M, Toppila I, Karlsson A, Veijalainen L, Idänpään-Heikkilä J and Laitinen T. Journal of Asthma (2019). DOI: 10.1080/02770903.2019.1633664. 

Heart failure in Finland: clinical characteristics, mortality, and healthcare resource use, Huusko J, Kurki S, Toppila I, Purmoen T, Lassenius M, Gullberg E, Bruce-Wirta S and Ukkonen H. ESC Heart Failure (2019). DOI: 10.1002/ehf2.12443.

Burden of migraine in Finland: health care resource use, sick-leaves and comorbidities in occupational health care, Korolainen M, Kurki S, Lassenius M, Toppila I, Costa-Scharplatz M, Purmonen T and Nissilä M. Journal of headache and pain (2019) 20:13. DOI: 10.1186/s10194-019-0964-5.

Type 2 diabetes and treatment intensification in primary care in Finland, Niskanen L, Hahl J, Haukka J, Leppä E, Miettinen T, Mushnikov V, Sipilä R, Tamminen N, Vattulainen P and Korhonen P. Acta Diabetologica (2018) 55:1171-1179.

Health care resource utilization and characteristics of patients with eosinophilic asthma in secondary health care in Finland, Mäkelä MJ, Christensen HN, Karlsson A, Rastogi S and Kettunen K. European Clinical Respiratory Journal (2018) 5(1):1458560.

The economic burden of severe COPD for health care in Finland. Manuscript in preparation.


Posters or oral presentations at international congresses

Migraine comorbidity and phenotypic disease networks in occupational health care. Korolainen M A, Kurki S, Tuominen S, Toppila I, Lassenius M I, Santaholma J, Purmonen T, Nissilä M. 19th Congress of the International Headache Society, Sep 7-8, 2019; Dublin, Ireland.  

Study to determine predictive potential of an algorithm for earlier diagnosis of Gaucher disease: Retrospective biobank study utilizing real-world data available in Finland. Savolainen M, Karlsson A, Toppila I, Elomaa K, Panahloo Z, Wolf M. 15th Annual WORLD Symposium, Feb 4-8, 2019; Orlando, Florida, USA.

Health Registry Data Survey for Assessing Characteristics and Descriptive Epidemiology of Patients with Multiple Myeloma in Southwest Finland between 2004—May 2017. Salmi T, Saukkonen K, Wolf, M, Toppila I, Kurki S, Schoonen M, Putkonen M. ESH, 4th International Conference on multiple myeloma, Oct 5-7, 2018; Mandelieu, France.

Health care resource use, sick-leaves and comorbidities among migraine patients in occupational healthcare. Korolainen M A, Kurki S, Toppila I, Lassenius M, Purmonen T, Nissilä M. European Head Ache federation meeting, Sep 28-30, 2018; Florence, Italy.

Heart Failure in Finland – Evaluating the burden of disease and treatment patterns. Huusko J, Kurki S, Toppila I, Purmonen T, Lassenius M, Gullberg E, Bruce-Wirta S, Ukkonen H. European Society of Cardiology Congress, 2018; Munich, Germany.

Trend towards longer time to reimbursement in oncological medicines in Finland 2005-2015. Oinonen L, Renlund M, Pudas H, Ihalmo P, Hahl J. ISPOR, 2016.

The epidemiology of adult immune (idiopathic) thrombocytopenic purpura (ITP) in Finland: resource utilisation, related costs and hospital medication associated with the treatment of non-splenectomised adult ITP based on real world data from Auria biobank. Kosunen M, Kurki S, Snicker K, Wiik E. ISPOR, 2017

Resource utilisation and related health care costs among patients with multiple myeloma with ≥ 2 prior lines of treatment in Finland: evaluation based on Finnish real world data from Auria biobank. Kosunen M, Kurki S, Snicker K, Wiik E. ISPOR, 2017

Resource use, health care costs and burden of disease in patients with polycythemia vera in Finland: evaluation based on leukocyte counts using Finnish real world data from Auria biobank. Kosunen M, Kurki S, Snicker K, Wiik E. ISPOR, 2017.

Cost-effectiveness of Pasireotide long-acting in a treatment of acromegaly in Finland economic evaluation based on Finnish Auria biobank data on health care resource utilization. Hahl J, Kurki S, Miettinen T, Snicker K. ISPOR, 2017.


Tutkimuksen uudet mahdollisuudet on huomioitava biopankkilaissa. Tuompo W, Hemmilä P, Ahlamaa J and Wolf M. Finnish Medical Journal (2018) 37: 2006-2007.


For more information about the publications, please be in contact with Mariann Lassenius.